The team of fish chronobiology at the University of Murcia has focused its research on the study of biological rhythms, their molecular origin (clock genes), their environmental synchronization (light and temperature cycles) and their effects on physiology and behavior. Both model fish and species of interest in aquaculture (sea bass, githead sea bream, sole and tilapia). The main research areas in which they have focused have been 1) nutrition and food, 2) reproduction, 3) early development and 4) wellness (stress and cytotoxicity). In addition, its on-demand and video recording systems for studying feeding, dietary and motor activity rhythms in specialized laboratories with environmental isolation (chronolabs) for marine and freshwater fish have been pioneers.
2009. Feeding entrainment of daily rhythms of locomotor activity and clock gene expression in zebrafish brain. Chronobiol Int 26: 1120-1135. Sánchez-Perez JA, Sánchez-Vázquez FJ.
2010. Feeding time synchronises daily rhythms of behaviour and digestive physiology in Gilthead sea bream (Sparus aurata). Aquaculture 306: 315-21. Montoya A, López-Olmeda JF, Yúfera M, Sánchez-Muros MJ, Sánchez-Vázquez FJ.
2010. Molecular cloning, tissue distribution and daily rhythms of expression of Per1 gene in European sea bass (Dicentrarchus labrax). Chronobiol Int 27: 19-33. Sánchez JA, Madrid JA, Sánchez-Vázquez
2010. Effect of daily thermo- and photo-cycles of different light spectrum on the development of Senegal sole (Solea senegalensis) larvae. Aquaculture 306: 137-45. Blanco-Vives B, Villamizar N, Ramos J, Bayarri MJ, Chereguini O, Sánchez-Vázquez FJ.
2010. Restricted feeding time resets per1 expression in the liver peripheral oscillator but not in the brain of zebrafish. Chrobiol Int 27: 1380-400. López-Olmeda JF, Tartaglione EV, de la Iglesia HO, Sánchez-Vázquez FJ.
2011. Prediction of fillet fatty acid composition of market-size gilthead sea bream (Sparus aurata) using a regression modelling approach. Aquaculture 319: 81-8. Ballester-Lozano GF, Benedito-Palos L, Navarro JC, Kaushik S, Pérez-Sánchez J.
2011. Does lighting manipulation during incubation affect hatching rhythms and early development of sole? Chronobiol Int 28(4): 300-6. Blanco-Vives B, Aliaga-Guerrero M, Cañavate JP, Muñoz-Cueto JA, Sánchez-Vázquez FJ.
2011. Macronutrient selection in Nile tilapia fed gelatin capsules and challenged with protein dilution/restriction. Physiol Behav 102: 356-60. Fortes-Silva R, Martínez FJ, Sánchez-Vázquez FJ.
2011. Exposure of larvae to daily thermocycles affects gonad development, sex ratio, and sexual steroids in Solea senegalensis, kaup. J Exp Zool 315: 162-9. Blanco-Vives B, Vera LM, Ramos J, Bayarri MJ, Mañanós E, Sánchez-Vázquez FJ.
2011. A blind circadian clock in cavefish reveals that opsins mediate peripheral clock photoreception. PLoS Biol 9(9): e1001142. Cavallari N, Frigato E, Vallone D, Fröhlich N, Lopez-Olmeda JF, Foà A, Berti R, Sánchez-Vázquez FJ, Bertolucci C, Foulkes NS.
2011. Behavioral responses of European sea bass (Dicentrarchus labrax) larvae and Artemia sp. exposed to constant light or darkness vs. light/dark cycles of white, red or blue wavelengths. Aquaculture 317: 197-202. Villamizara N, García-Mateos G, Sánchez-Vázquez FJ.
2011. Self-selection of diets with different oil oxidation levels in gilthead sea bream (Sparus aurata). Aquaculture 314: 282-84. Montoya A, Alves Martins D, Yúfera M, Sánchez-Vázquez FJ.
2011. Impact of photoperiod manipulation on day/night changes in melatonin, sex steroids and vitellogenin plasma levels and spawning rhythms in Senegal sole, Solea senegalensis. Comp Biochem Physiol A 159: 291-95. Oliveira C, Mañanós E, Ramos J, Sánchez-Vázquez FJ.
2012. Effect of daily thermocycles on embryonic and larval development, survival, behaviour and sex differentiation of zebrafish (Danio rerio). PLoS ONE 7(12): e52153. Villamizar N, Ribas L, Piferrer F, Vera LM, Sánchez-Vázquez FJ.
2012. Does feeding time affect fish welfare? Fish Physiol Biochem 38: 143-152. López-Olmeda JF, Noble C, Sánchez-Vázquez FJ.
2012. Demand feeding and welfare in farmed fish. Fish Physiol Biochem 38: 107-118. Attia J, Millot S, Di-Po C, Bégout ML, Noble C, Sanchez-Vazquez FJ, Terova G, Saroglia M, Damsgård B.
2012. Dietary self-selection of protein-unbalanced diets supplemented with three essential aminoacids in Nile tilapia. Physiol Behav 105: 639-44. Fortes R, Vieira P, Zamora S, Sánchez-Vázquez FJ.
2012. Use of self-feeders to evaluate macronutrient self-selection and energy intake regulation in Nile tilapia. Aquaculture 326-329: 168-72. Fortes R, Sánchez-Vázquez FJ.
2012. Dietary self-selection in gilthead sea bream (Sparus aurata): target intake defense and protein deprivation response. Aquaculture 358-359: 35-40. Montoya A, Zamora S, Sánchez-Vázquez FJ.
2012. Daily rhythms of clock gene expression, glycaemia and digestive physiology in diurnal/nocturnal European sea bass. Physiol Behav 106: 446-50. Del Pozo A, Montoya A Vera LM, Sánchez-Vázquez FJ.
2012. Impact of a telemetry-transmitter implant on daily behavioral rhythms and physiological stress indicators in gilthead sea bream (Sparus aurata). Marine Environ Res 79: 48-54. Montoya A, López-Olmeda JF, López-Cape, JA, Sánchez-Vázquez FJ, Perez-Ruzafa A.
2012. Daily spawning and locomotor activity rhythms of European sea bass brood stock (Dicentrarchus labrax). Aquaculture. 354-355: 117-20. Villamizar N, Herlin M, López M, Sánchez-Vázquez FJ.
2012. Metamorphosis induces a light-dependent switch in Senegalese sole (Solea senegalensis) from diurnal to nocturnal behavior. J Biol Rhythms 27: 135-44. Blanco-Vives B, Aliaga-Guerrero M, Cañavate JP, García-Mateos G, Martín-Robles AJ, Herrera-Pérez P, Muñoz-Cueto JA, Sánchez-Vázquez FJ.
2012. Daily rhythms of digestive physiology, metabolism and behaviour in the European eel (Anguilla anguilla). Aquaculture Int 20: 1085-96. López-Olmeda JF, López-García I, Sánchez-Muros MJ, Blanco-Vives B, Aparicio R, Sánchez-Vázquez FJ.
2012. Circadian clocks: Lessons from fish. Progress Brain Res 199: 49-57. Idda ML, Bertolucci C, Vallone D, Gothilf Y, Sánchez-Vázquez FJ, Foulkes NS.
2012. Molecular cloning, tissue distribution and daily expression of cry1 and cry2 clock genes in European sea bass (Dicentrarchus labrax). Comp Biochem Physiol 163A: 364-71. Del Pozo A, Vera LM, Sánchez JA, Sánchez-Vázquez FJ.
2012. Self-selection of diets with different contents of arachidonic acid by Senegalese sole (Solea senegalensis) brood stock. Aquaculture. 364-365: 198-205. Norambuena F, Estévez A, Sánchez-Vázquez FJ, Carazo I, Duncan N.
2012. Impact of daily thermocycles on hatching rhythms, larval performance and sex differentiation of zebrafish. PLoS ONE 7: e52153. Villamizar N, Ribas L, Piferrer F, Vera LM, Sánchez-Vázquez FJ.
2013. Daily rhythms of blood glucose and feeding behavior differed in diurnal and nocturnal European sea bass (Dicentrarchus labrax L.) undergoing seasonal phase inversions. Fish Physiol Biochem 39: 695-99. Del Pozo A, Vera LM, Montoya A, Sánchez-Vázquez FJ.
2013. Endocrine (plasma cortisol and glucose) and behavioral (locomotor and self-feeding activity) circadian rhythms in Senegalese sole (Solea senegalensis Kaup 1858) exposed to light/dark cycles or constant light. Fish Physiol Biochem 39(3): 479-87. Oliveira C, Aparício R, Cherenguini O, Martín I, Sánchez-Vázquez FJ.
2013. Daily rhythms in the hypothalamus-pituitary-interrenal axis and acute stress responses in a teleost flatfish, Solea senegalensis. Chronobiol 30(4): 530-9. López-Olmeda JF, Blanco-Vives B, Pujante IM, Wunderink YS, Mancera JM, Sánchez-Vázquez FJ.
2013. Effectiveness of the anaesthetic MS-222 in gilthead sea bream, Sparus aurata: effect of feeding time and day-night variations in plasma MS-222 concentration and GST activity. Physiol Behavior 110-11: 51-7. Vera LM, Montoya A, Sánchez-Vázquez FJ.
2013. Circadian rhythms of embryonic development and hatching in fish: A comparative study of Zebrafish (diurnal), Senegalese sole (nocturnal) and Somalian cavefish (blind). Chronobiol Int 30: 889-900. Villamizar N, Blanco-Vives B, Oliveira C, Dinis MT, Di Rosa V, Negrini P, Bertolucci C, Sánchez-Vázquez FJ.
2013. The effect of night illumination, red and infrared light, on locomotor activity, behaviour and melatonin of Senegalese sole (Solea senegalensis) brood stock. Physiol Behavior 118: 201-7. Carazo I, Norambuena F, Oliveira C, Sánchez-Vázquez FJ, Duncan N.
2013. ERK signaling regulates light-induced gene expression via D-Box enhancers in a differential, wavelength-dependent manner. PLoS One 8: e67858. Mracek P, Pagano C, Fröhlich N, Idda ML, Cuesta IH, Lopez-Olmeda JF, Sánchez-Vázquez FJ, Vallone D, Foulkes NS.
2014. Effect of feeding frequency on the daily rhythms of acidic digestion in a teleost fish (gilthead sea bream). Chronobiol Int 31: 1024-33. Yúfera M, Romero MJ, Pujante IM, Astola A, Mancera JM, Sánchez-Vázquez FJ, Moyano FJ, Martínez-Rodríguez G.
2014. Acute stress response in gilthead sea bream (Sparus aurata L.) is time-of-day dependent: Physiological and oxidative stress indicators. Chronobiol Int 31: 1051-61. Vera LM, Montoya A, Pujante IM, Pérez-Sánchez J, Calduch-Giner JA, Mancera JM, Moliner J, Sánchez-Vázquez FJ.
2015. Daily rhythms of clock gene expression and feeding behavior during the larval development in gilthead seabream, Sparus aurata. Chronobiol Int 32(8):1061-74. Mata-Sotres JA, Martínez-Rodríguez G, Pérez-Sánchez J, Sánchez-Vázquez FJ, Yúfera M.
2010. Feeding rhythms in fish: from behavioral to molecular approach. Biological clock in fish. Editores: E. kulczykowska; Science Publishers, Enfield, USA (860 pp). Chapter: 8: 155-184. López-Olmeda JF, Sánchez-Vázquez FJ.
2010. Reproduction rhythms in fish. Biological clock in fish. Ed. E. kulczykowska; Science Publishers, Enfield, USA (860 pp). Chapter 9: 185-216. Oliveira C, Sánchez -Váquez FJ.
2012. Nutrition and diet choice. Aquaculture & Behavior (Edts. Felicity Huntingford, Sunil Kadri, Malcom Jobling). Wiley-Blackwell. Capítulo: 6. 150-182. Raubenheimer B, Simpson S, Sanchez-Vazquez FJ, Huntingford FA, Kadri S, Jobling M.
2012. Appetite and feed intake. Aquaculture & Behavior (Edts. Felicity Huntingford, Sunil Kadri, Malcom Jobling). Wiley-Blackwell. Capítulo: 7. 183-219. Jobling M, Alanara A, Noble C, Sanchez-Vazquez FJ, Kadri S, Huntingford FA.
2013. The biology of sea bass. Sánchez-Vázquez FJ, Muñoz-Cueto JA (Eds.). Science Publishers Hampshire, USA. Sánchez-Vázquez FJ, Muñoz-Cueto JA.
2009. Effect of light spectrum and photoperiod on the growth, development and survival of European sea bass (Dicentrarchus labrax) and Atlantic cod (K) larvae. LARVI 2009. 5th fish & shellfish larviculture symposium. Gante (Belgium).
2010. Daily rhythm of behavioural, hormonal and digestive activity in the gilthead sea bream (Sparus aurata): Influence of feeding schedules. 9th International Congress on the Biology of Fish. American Fish Society, Barcelona (Spain), 5-9 July. López-Olmeda FJ, Montoya A, Yúfera M, Sánchez-Muros MJ, Garayzar ABS, Sánchez-Vázquez FJ.
2010. Improvement of aquaculture production by the use of biotechnological tools (AQUAGENOMICS). Aquaculture Europe 2010. Porto (Portugal), 5-8 Octubre. Novoa B, Martínez P, Piferrer F, Mackenzie S, Planas JV, Morán F, Toranzo AE, Mulero V, Sanchez FJ, Estepa A, Coll J, Tort L, Yufera M, Pérez J, Zanuy S, Cerdá JM, Toro MA, Rejón MR, Figueras A.
2011. Effect of feeding protocol on daily acidic digestion in gilthead sea bream juveniles. Aquaculture Europe 2011, Rhodes (Greece) 18-21 October. Yúfera M, Romero MJ, Moyano FJ, Sánchez-Vázquez FJ, Mancera JM, Martínez-Rodríguez G.
2012. Influence of photoperiod on circadian rhythms and intensive fish farming. 49th Congress of the Brasilian Society of Animal Science. Brasilia (Brasil). Sánchez Vázquez FJ.
2012. Daily thermocycles alter larval development and sex differentiation of fish. II Conference on Conservation and Physiology of Marine Fishes. COST Action FA 1004, Pula (Croacia), 24-26 Septiembre. Villamizar N, Blanco-Vives LM, Vera LM, Ramos M, Bayarri MJ, Ribas L, Piferrer F, Mañanós E, Sánchez-Vázquez FJ.
2010. Dual phasing rhythms in fish. 26th Congress of the International Society for Chronobiology. Vigo (Spain). Sánchez Vázquez, FJ
2009. José Fernando López. University of Murcia. Circadian modulation of the biological clock and behavioral, endocrine and metabolic rhythms of teleostean fishes. Director Sánchez-Vázquez FJ.
2010. Rodrigo Fortes da Silva. University of Murcia. Estudio comparado de los ritmos de alimentación y selección dietaria en dos peces teleósteos: lubina y tilapia del Nilo. Director Sánchez-Vázquez FJ.
2012. Borja Blanco Vives. University Cardenal Herrera. Daily rhythms of spawning and early larval development of zebrafish and sole: impact of light and thermocycles. Directores Sánchez-Vázquez FJ, Muñoz Cueto JA.
2012. Ander Montoya Herreros. University of Murcia. Ritmos diarios de comportamiento alimentario y bienestar en la dorada (Sparus aurata). Directores Sánchez-Vázquez FJ, Lopez Olmeda JF.
2012. Natalia Villamizar Villamizar. University of Murcia. Influencia de la luz y temperatura sobre la ontogenia del reloj biológico y ritmos de actividad de la lubina (Dicentrarchus labrax). Director Sánchez-Vázquez FJ.
2013. Ana del Pozo Cano. University of Murcia. Influence of light and feeding patterns on the molecular clock, digestive physiology and behaviour of two teleost fishes: sea bass (Dicentrarchus labrax) and zebrafish (Danio rerio). Director Sánchez-Vázquez FJ.
COST Action FA1004. Conservation physiology of marine fish.
COST Action FA1205. Assessing and improving the quality of aquatic animal gametes to enhance aquatic resources – The need to harmonize and standardize evolving methodologies, and improve transfer from academia to industry.
COST Action FA1305. The EU Aquaponics HUB: Realising Sustainable Integrated Fish and Vegetable Production for the EU.
Integrated Actions (IT2009-0057, Germany; DE2009-0045, Italy). Fish chronobiology network: ontogeny of the biological clock and reproduction rhythms.
Contract for the optimization of the seabass larvae culture: influence of the circadians cycles. AQUICULTURA BALEAR (CULMAREX group).